A research team of Banaras Hindu University (BHU) has found that a Neem plant component can help fight cancer.
The research team has reported the in-vitro and in-vivo therapeutic efficacy of nimbolide (a bioactive component of Neem plant) against T-cell lymphoma, which is a cancer of immune cells. It has strongly advocated the utility of nimbolide as a potential anti-cancer therapeutic drug for the treatment of haematological malignancies.
According to BHU Spokesperson Rajesh Singh, the novel findings of this study have been published in two parts in a reputed international journal 'Environmental Toxicology'.
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The study was done by research student Pradip Kumar Jaiswara along with researchers Vishal Kumar Gupta, Rajan Kumar Tiwari and Shiv Govind Rawat, and was funded by the UGC Start-up Research Grant.
The researchers said Neem (Azadirachta indica) is a traditional medicinal plant, flowers and leaves of which are widely used as a traditional medicine for the treatment of several diseases due to its various pharmacological properties, including anti-parasitic, anti-bacterial, anti-viral, anti-inflammatory, anti-oxidant, anti-feedant and anti-allergic activity in India and Africa.
Recently, nimbolide, a bioactive component isolated from leaves and flowers of the Neem, and has been identified as one of the crucial molecules behind its medicinal values. The anti-tumour efficacy of nimbolide has only been evaluated against a few cancers.