After losing four times in finals, early exits in major tournaments and even a decision to retire from the national team, the superstar celebrated a much-awaited title with Argentina at Saturday's 1-0 win against Brazil in the Maracana Stadium.
The title ended Argentina's 28-year drought of major trophies, with Messi as the best player with four goals and five assists. The captain also broke the team's record for international appearances with 151 matches.
When Uruguayan referee Esteban Ostojich blew the final whistle, Messi knelt down on the pitch and covered his face with his hands.
The next challenge is to win the World Cup in Qatar next year, which would be the first since Maradona took the team to glory in 1986.
Until Saturday, Messi's titles with Argentina were only the U-20 World Cup title in 2005 and a gold medal at the Beijing Olympics in 2008.
On Saturday Messi kissed the Copa America trophy and lifted it at age 34. The biggest gap in his decorated career is now closed.
Football fans across the world had eyes set on the game with fingers crossed. Messi fans are celebrating the occasion with much gusto.
Have a look.