COVID-19 Vaccine: Germany's expert panel recommends giving AstraZeneca shots only to those under 65 years of age

COVID-19 Vaccine: Germany's expert panel recommends giving AstraZeneca shots only to those under 65 years of age

Associated PressUpdated: Friday, January 29, 2021, 05:00 PM IST
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Vials with Covid-19 Vaccine stickers attached and syringes, with the logo of the University of Oxford and its partner British pharmaceutical company AstraZeneca. | AFP Photo

Berlin: A draft recommendation from Germany's vaccination advisory committee calls for offering the AstraZeneca vaccine only to people aged 18-64 for now, citing what it says is insufficient data to judge its effectiveness for older people.

The European Medicines Agency is expected to approve the AstraZeneca vaccine for use in the 27-nation European Union on Friday. It would be the third cleared for use in the EU after the BioNTech-Pfizer and Moderna vaccines.

In a draft recommendation released on Thursday ahead of that decision, Germany's permanent vaccination commission called for using AstraZeneca's vaccine for the 18-64 age group on the basis of currently available information. It said that "there currently is not sufficient data to assess the vaccination effectiveness from 65 years." AstraZeneca noted earlier this week that British regulators supported its use in the older age group despite lack of late-stage effectiveness data. The company pointed to earlier-stage data published in the journal Lancet in November "demonstrating that older adults showed strong immune responses to the vaccine, with 100% of older adults generating spike-specific antibodies after the second dose." But questions remain about how well the vaccine protects older people.

Only 12 per cent of participants in the AstraZeneca research were over 55 and they were enrolled later, so there hasn't been enough time to see whether they get sick at a lower rate than those who didn't get the vaccine.

German Health Minister Jens Spahn stressed that the committee's recommendation isn't its final decision, and that will be made only after the vaccine is cleared for use.

But he said there had been a discussion since autumn about there being "few data - this isn't about bad data, but few data" in studies on the AstraZeneca vaccine's effectiveness in older groups.

"It was to be expected that this would have an influence on the decision of the regulatory authorities and then the permanent vaccine commission," Spahn said. "We just don't know yet how concretely -- so let's wait for the decision tomorrow on clearance and then the final recommendation from the permanent vaccine commission." When Britain approved the AstraZeneca vaccine for emergency use last month, it acknowledged that data regarding its effectiveness in older people was "limited."

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