According to a recent study conducted by All India Institute Of Medical Sciences (AIIMS) in Delhi during April to May 2021, it was found that none of the vaccinated people had threat to life after getting re-infected with the COVID-19 virus. And that the disease was a rarity amongst those who were vaccinated.
AIIMS and CSIR-Institute of Genomics and Integrative Biology jointly analyzed 63 cases, mainly healthcare workers at the hospital itself.
Out of the 63 breakthrough infections, 36 patients received two doses, while 27 received at least one dose of the Covid-19 vaccine. Ten patients received Covishield, while 53 received Covaxin.
Of the 63 cases of vaccine breakthrough infections, including 36 who received full doses, there were no reports of mortality even though almost all cases presented with high-grade unremitting fever for 5-7 days, it added.
“While antibody levels for a subset of patients were available, they became infected nevertheless and presented to the emergency just like other patients, putting in doubt the protection offered and or clinical relevance of total IgG as a surrogate of Covid-19 immunity. The present report is unique in many aspects,” the AIIMS report stated.
The patients ranged in age from 21 to 92 years old, with 41 men and 22 women. There were no comorbidities in any of the participants that could have acted as a risk factor for infection.
Ten patients developed total Immunoglobulin G (IgG) antibodies, evaluated by Chemiluminescent Immunoassay, in these breakthrough infections, eight with double vaccine doses and two with single doses.