Need to end ‘missed opportunities’ in AIDS battle

Factors like lack of accountability, sub-optimal programme effectiveness, and complacency are slowing us down from reaching the goal of an AIDS-free world

Dr Ishwar GiladaUpdated: Thursday, December 01, 2022, 10:48 AM IST
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World AIDS Day, observed globally on December 1 since 1989, is an occasion to take stock and reflect upon what has been achieved towards the prevention, control and management of HIV/AIDS and where we lag behind. There is no doubt that the achievements have been phenomenal in saving millions of lives and preventing many more from getting HIV infections, globally during the past two decades. India has also done well, not only for itself but also by making anti-retroviral therapy (ART) affordable and accessible to over 90% of people living with HIV (PLHIV) in the world. However our goals are high and still far from being achieved.

We have adequate and efficient tools to end AIDS, whether science-backed tools and approaches to prevent HIV transmission, or diagnosing and treating PLHIV so that they can live healthy and fulfilling lives. With these tools, we are progressing — but not progressing as fast as we should to end AIDS by 2030. An array of “missed opportunities” is plaguing the AIDS response worldwide. Factors like lack of accountability, sub-optimal programme effectiveness, and complacency are slowing us down from reaching the goal of an AIDS-free world. The Covid-19 pandemic did play spoilsport, but we cannot use it as an excuse towards non-achievement of goals.

We have robust ART, that can result in undetectable viral load for those PLHIV on treatment within just a couple of months, and by now it is amply clear that “Undetectable is Untransmittable” or U=U. Thus, each new HIV case is a missed opportunity where a range of combination prevention options could have helped prevent the person from getting infected. Likewise, every AIDS-related death is a grim reminder that it could have been averted because we have proven science-backed tools to make AIDS death history.

The World AIDS Day 2022 theme is “Equalize”. We will have to end the inequalities which perpetuate the AIDS pandemic. The “Equalize” slogan of UNAIDS is a call to action for all of us to work for the proven practical actions needed to address inequalities to help end AIDS. All PLHIV must have access to HIV testing and treatment. Laws and policies should help end (and not abet) stigma and discrimination faced by people living with HIV and by key and marginalised populations, and laws like India’s HIV/AIDS ACT 2017 should not remain a toothless weapon.

The United Nations Sustainable Development Goals (UN SDGs) as well as the National Health Policy of India promised that by 2020, 90% of people living with HIV will know their status, 90% of these will have access to ART and 90% of those on ART will have viral suppression.

Most countries were not able to deliver on 2020 HIV targets of 90-90-90 but made commendable progress. Conveniently shifting goalposts will not help end AIDS.We can end AIDS by 2030 but the curve will not bend by itself. We need to remember that we could have achieved these goals had we succeeded in eliminating missed opportunities in the AIDS response. We should have ensured that the full HIV combination prevention spectrum and complete range of diagnostics, treatment, care and support services were reaching everyone, especially those among the key populations. Ending AIDS is one of the targets of the UN SDGs. Unless we progress on all goals and targets, we will not be able to progress towards ending AIDS as we should.

Globally, the data for 2021 shows that 38.4 million people were living with HIV, out of which 1.7 million were children; 54% of all people living with HIV were women and girls. In 2021, 650,000 people died of AIDS-related causes — one every minute — despite effective HIV treatment and tools to prevent, detect and treat opportunistic infections such as cryptococcal meningitis and TB. These are preventable deaths.

An astonishing 1.5 million people became newly infected with HIV in 2021 — ie, 4000 new infections every day. The number of people onHIV treatment increased by only 1.47 million in 2021, compared to net increases of more than 2 million people in previous years. Globally, 85% of all people living with HIV knew their HIV status in 2021. Among people who knew their status, 88% were accessing treatment. And among people accessing treatment, 92% were virally suppressed. In other words of all people living with HIV 85% knew their status, 75% were accessing treatment and 68% were virally suppressed in 2021.

According to UNAIDS, an estimated 2.4 million people were living with HIV in India in 2021 (including 70,000 children). Out of these 1.9 million or 77% knew their HIV status; 1.6 million (or 65% of 2.4 million) were on lifesaving antiretroviral therapy; and 1.3 million (or 55% of 2.4 million) had suppressed viral load. More alarmingly, 63,000 people were newly infected with HIV in 2021 in India — 173 new infections every day or seven infections every hour. And sadly, there were 42,000 AIDS-related deaths in 2021 (five deaths every hour).

In the journey towards #endAIDS goals, one of the earlier milestones has to be elimination of parent-to-child transmission of HIV (or vertical transmission of HIV), as that doesn’t even need change in behaviour unlike sexual mode of transmission. India, despite progress towards eliminating parent-to-child transmission of HIV, is yet to achieve this goal. Coverage of pregnant women who receive medicines to prevent HIV transmission to the unborn child (during pregnancy or breastfeeding) is 64%. Vertical transmission rate including during breastfeeding 24.3%. This is another missed opportunity which we truly cannot afford to ignore if we are to end AIDS in the next 96 months (by 2030); rather, we should completely eliminate parent-to-child transmission of HIV as early as possible.

Data-backed science has long raised the alarm on low coverage of HIV services among those who are most at risk, such as the key populations. Needless to say, we have to scale up the HIV response especially for those who are at relatively higher risk. While overall HIV prevalence in adults in India is 0.24%, HIV prevalence in sex workers is 1.9%; in gay men and other men who have sex with men (MSM) it is 3.3%; in transgender people it is 3.85%, and in people who inject drugs it is 9%. Whereas HIV prevalence in prisoners is 1.9% but coverage of anti-retroviral therapy is only 28.7% in prisoners.

Amidst calls to #endAIDS globally, let us remember that business as usual will fail us. If current trends continue, more than 1.2 million people will be newly infected with HIV in 2025 — three times more than the pre-set target of 370,000 new infections by 2025.

India’s capacity to produce generic HIV medicines and supply them worldwide did result in major successes for the global AIDS fight, as over 90% of anti-retrovirals consumed globally were from India. We have the time-tested and proven capacity to manufacture HIV diagnostics and medicines, and robust supply chain mechanisms to deliver them worldwide, sustainably. But are HIV programmes worldwide strong enough to ensure that HIV prevention, diagnostics, treatment, care and support services are reaching every person in need – without any further delay?

The next best opportunity to eliminate the difference between “what we know works” and “what we do” is now. We know how to prevent HIV, diagnose HIV, treat, care and support PLHIV. But the gap between where we are and where we need to be, or “what we can do” and the ground reality, is a chasm we cannot afford to have any more. Bridge the gap to end AIDS. At least make a good beginning from this World AIDS Day. The 14th National Conference of the AIDS Society of India, to cover HIV and emerging infections and with the theme “EnergiZe – EmpathiZe – EqualiZe”, will be held at ITC WelcomHotel, Delhi from March 17 to 19, 2023 and will deliberate these issues threadbare with ace international and national faculty and policy-makers on board.

Dr Ishwar Gilada is Secretary General, Peoples Health Organisation; President, AIDS Society of India (ASI) and Governing Council member of International AIDS Society (IAS), www.asi-asicon.com. He can be contacted at gilada@usa.net

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