UK begins trial of Gritstone's GRT-R910 multi-variant COVID-19 booster vaccine

IANSUpdated: Tuesday, September 21, 2021, 06:06 PM IST
article-image

The UK has kicked off a trial of what has been described as the world's first multi-variant vaccine booster against Covid-19 in the city of Manchester. On Monday, a married couple, both in their 60s, became the first participants in the trial, a collaboration between the University of Manchester and a National Health Service (NHS) foundation trust in the city, reports Xinhua news agency.

Launched by US pharmaceutical company Gritstone, the drug, called GRT-R910, is claimed to boost the immune response of first-generation Covid-19 vaccines to a wide array of variants of Sars-Cov-2, which cause the disease.

The phase one trial of the vaccine is taking place at the National Institute for Health Research Manchester Clinical Research Facility at Manchester Royal Infirmary.

A spokesman for the University of Manchester said data evaluating the vaccine is expected in the first quarter of 2022, with results from the pre-clinical studies published later in the year.

"We now know the immune response to first generation vaccines can wane, particularly in older people. Coupled with the prevalence of emerging variants, there is a clear need for continued vigilance to keep Covid-19 at bay," said Andrew Ustianowski, clinical lead for the vaccine research program.

"We think GRT-R910 as a booster vaccination will elicit strong, durable, and broad immune responses, which are likely to be critical in maintaining protection of this vulnerable elderly population who are particularly at risk of hospitalisation and death," Ustianowski added.

More than 89 per cent of people aged 16 and over in the UK have had their first dose of Covid vaccine and more than 81 per cent fully inoculated against the virus, the latest figures showed.

(If you have a story in and around Mumbai, you have our ears, be a citizen journalist and send us your story here. )

(To receive our E-paper on WhatsApp daily, please click here.  To receive it on Telegram, please click here. We permit sharing of the paper's PDF on WhatsApp and other social media platforms.)

RECENT STORIES

Watch: Birds displayed unusual behaviour just moments before devastating earthquake in Turkey

Watch: Birds displayed unusual behaviour just moments before devastating earthquake in Turkey

Turkey earthquake: Schools, colleges, in Turkey, Syria closed as three powerful quakes leave over...

Turkey earthquake: Schools, colleges, in Turkey, Syria closed as three powerful quakes leave over...

Earthquake of magnitude 3.8 hits New York, strongest jolt in 40 years

Earthquake of magnitude 3.8 hits New York, strongest jolt in 40 years

Nepal Plane Crash: Probe reveals engine trouble as reason behind Yeti Airlines accident

Nepal Plane Crash: Probe reveals engine trouble as reason behind Yeti Airlines accident

Turkey Earthquake: Former Chelsea footballer Christian Atsu reportedly trapped under rubble

Turkey Earthquake: Former Chelsea footballer Christian Atsu reportedly trapped under rubble