Free Press Journal

Prostate cancer: hormone therapy ups depression


New York :  Elderly men being treated with hormone therapy for prostate cancer are likely to experience an increased risk of depression, a study has found, says IANS.

Researchers have found a significant association between depression and patients being treated for localised prostate cancer (PCa) by androgen deprivation therapy (ADT). “We know that patients on hormone therapy often experience decreased sexual function, weight gain and have less energy — many factors that can lead to depression,” said senior study author Paul Nguyen from Brigham And Women’s Hospital in the US.

“After taking a deeper look, we discovered a significant association between men being treated with ADT for PCa and depression,” Nguyen added. The team analysed 552 men over the age of 65 with stage I to III PCa from 1992 to 2006 of 78. They investigated the association between ADT and a diagnosis of depression or confirmation of inpatient or outpatient psychiatric treatment and compared to patients who did not receive the therapy.